Here is a quick Tip.

For a command-line junkie like me, this is a geeky fun way to scan your system with spybot with CMD, with few easy parameters. For a spyware only version of the scan I used this parameters:
“C:\Program Files\Spybot - Search &
Destroy\SpybotSD.exe” /taskbarhide /autoclose /autocheck /autofix /onlyspyware

For a list of other available parameters, (from Spybot website):

• /taskbarhide
  Runs Spybot-S&D completely hidden (no window, no taskbar icon), so make absolutely sure you use it only in combination with /autoclose (otherwise it would remain in memory sitting idle). Useful only in combination with /autocheck, /autoupdate or /autoimmunize, as it cannot be controlled when completely invisible.
• /minimized
  Starts the window minimized.
• /uninstall
  Uninstalls Spybot-S&D. This command line parameter is very outdated - unins000.exe should be used instead!
• /blinduser
  Starts with support for blind users (special menus).
• /autoupdate
  Does an update after starting the program.
• /autocheck
  Starts scanning immediately.
• /autofix
  Fixes problems after scan.
• /autoclose
  Closes program after it has scanned or updated.
• /autoimmunize
  Runs the immunization at program start.
• /onlyspyware
  Fixes only spyware (red) entries with /autofix, leaving all usage tracks as they are.
• /easymode
  Starts with easier interface for beginners.
• /createenglish
  Updates the English.sbl language file with the newest texts; useful only for translators.